A trephine is a surgical instrument with a cylindrical blade. It can be of one of several dimensions and designs depending on what it is meant to be used for. A trephine may be specially designed for
A trephine with a center pin can be seen on the left.
Dr. John Clarke trepanning a skull, ca. 1664, in one of the earliest American portraits. Clarke has a trephine in his right hand. The painting is in Harvard Medical School.