Trou au Natron or Doon Orei is a volcanic caldera of the Tibesti Massif in the nation of Chad in Northern Africa. The volcano is extinct. It is unknown when it last erupted. Its volcano number is 0205–01. Trou au Natron is located just south-east of Toussidé, the westernmost volcano of the Tibesti Mountains. Its edge cuts into the nearby Yirrigue caldera.

The Tibesti Mountains are a mountain range in the central Sahara, primarily located in the extreme north of Chad, with a small portion located in southern Libya. The highest peak in the range, Emi Koussi, lies to the south at a height of 3,415 meters (11,204 ft) and is the highest point in both Chad and the Sahara. Bikku Bitti, the highest peak in Libya, is located in the north of the range. The central third of the Tibesti is of volcanic origin and consists of five volcanoes topped by large depressions: Emi Koussi, Tarso Toon, Tarso Voon, Tarso Yega and Toussidé. Major lava flows have formed vast plateaus that overlie Paleozoic sandstone. The volcanic activity was the result of a continental hotspot that arose during the Oligocene and continued in some places until the Holocene, creating fumaroles, hot springs, mud pools and deposits of natron and sulfur. Erosion has shaped volcanic spires and carved an extensive network of canyons through which run rivers subject to highly irregular flows that are rapidly lost to the desert sands.