U.S. Route 70 (US 70), also known as the Old West Highway, is an east–west U.S. Highway in the U.S. state of Arizona. The current route starts at US 60 in Globe and runs through the San Carlos Indian Reservation, Safford and Duncan into New Mexico near Virden. In Arizona, US 70 passes through mostly isolated hilly and mountainous terrain largely paralleling the course of the Gila River and the Arizona Eastern Railway.

U.S. Route 66 also known as the Will Rogers Highway, was a major United States Numbered Highway in the state of Arizona from November 11, 1926, to June 26, 1985. US 66 covered a total of 385.20 miles (619.92 km) through Arizona. The highway ran from west to east, starting in Needles, California, through Kingman and Seligman to the New Mexico state line. Nationally, US 66 ran from Santa Monica, California, to Chicago, Illinois. In its height of popularity, US 66 was one of the most popular highways in the state of Arizona, sometimes carrying over one million cars a year.