U.S. Highway 77 (US-77) in Oklahoma is a 267.21-mile-long (430.03 km) U.S. Highway in the U.S. state of Oklahoma. It travels from south to north, paralleling Interstate 35 (I-35), connecting Texas to Kansas through the central part of the state. It travels through many major cities, including Ardmore, Oklahoma City and its suburbs, Guthrie, and Ponca City. It has four lettered spur routes.

Wynnewood is a city in Garvin County, Oklahoma, United States. It is 67 miles (108 km) south of Oklahoma City. The population was 1,927 at the time of the 2020 census. Located in what was then the Chickasaw Nation of Indian Territory, it began as a village called "Walner" in 1886, on the proposed route of the Gulf, Colorado and Santa Fe Railway. Railroad workers from Pennsylvania named the community for Wynnewood, a community outside of Philadelphia. The name became official on April 6, 1887.