The Umayyad Caliphate or Umayyad Empire was the second caliphate established after the death of the Islamic prophet Muhammad and was ruled by the Umayyad dynasty. Uthman ibn Affan, the third of the Rashidun caliphs, was also a member of the clan. The family established dynastic, hereditary rule with Mu'awiya I, the long-time governor of Greater Syria, who became caliph after the end of the First Fitna in 661. After Mu'awiya's death in 680, conflicts over the succession resulted in the Second Fitna, and power eventually fell to Marwan I, from another branch of the clan. Syria remained the Umayyads' main power base thereafter, with Damascus as their capital.

A caliphate or khilāfah is an institution or public office under the leadership of an Islamic steward with the title of caliph, a person considered a political-religious successor to the Islamic prophet Muhammad and a leader of the entire Muslim world (ummah). Historically, the caliphates were polities based on Islam which developed into multi-ethnic trans-national empires. During the medieval period, three major caliphates succeeded each other: the Rashidun Caliphate (632–661), the Umayyad Caliphate (661–750), and the Abbasid Caliphate (750–1517). In the fourth major caliphate, the Ottoman Caliphate, the rulers of the Ottoman Empire claimed caliphal authority from 1517 until the caliphate was formally abolished as part of the 1924 secularisation of Turkey. Throughout the history of Islam, a few other Muslim states, almost all of which were hereditary monarchies such as the Mamluk Sultanate and Ayyubid Sultanate, have claimed to be caliphates.