The United Charities Building, also known as United Charities Building Complex, is at 105 East 22nd Street or 287 Park Avenue South, in the Gramercy Park neighborhood of Manhattan, New York City, near the border of the Flatiron District. It was built in 1893 by John Stewart Kennedy, a wealthy banker, for the Charity Organization Society. It was designated a National Historic Landmark in 1991 for the role the Charity Organization Society played in promoting progressive social welfare policies, including the development of academic disciplines in that area.

Park Avenue is a boulevard in New York City that carries north and southbound traffic in the boroughs of Manhattan and the Bronx. For most of the road's length in Manhattan, it runs parallel to Madison Avenue to the west and Lexington Avenue to the east. Park Avenue's entire length was formerly called Fourth Avenue; the title still applies to the section between Cooper Square and 14th Street. The avenue is called Union Square East between 14th and 17th Streets, and Park Avenue South between 17th and 32nd Streets.