The United States secretary of state (SecState) is a member of the executive branch of the federal government and the head of the Department of State. The office holder is the second-highest-ranking member of the president's Cabinet, after the vice president, and ranks fourth in the presidential line of succession; first amongst cabinet secretaries.

The United States secretary of the treasury is the head of the United States Department of the Treasury, and is the chief financial officer of the federal government of the United States. The secretary of the treasury serves as the principal advisor to the president of the United States on all matters pertaining to economic and fiscal policy. The secretary is, by custom, a member of the president's cabinet and, by law, a member of the National Security Council.