The University of the Witwatersrand, Johannesburg, commonly known as Wits University or Wits, is a multi-campus public research university situated in the northern areas of central Johannesburg, South Africa. The university has its roots in the mining industry, as do Johannesburg and the Witwatersrand in general. Founded in 1896 as the South African School of Mines in Kimberley, it is the third oldest South African university in continuous operation.

Johannesburg is the most populous city in South Africa with 4,803,262 people, and is classified as a megacity; it is one of the 100 largest urban areas in the world. It is the provincial capital and largest city of Gauteng, which is the wealthiest province in South Africa. Johannesburg is the seat of the Constitutional Court, the highest court in South Africa. Most of the major South African companies and banks have their head offices in Johannesburg. The city is located within the mineral-rich Witwatersrand hills, the epicentre of the international-scale mineral, gold and (specifically) diamond trade.