Uptown is a section of New Orleans, Louisiana, United States, on the east bank of the Mississippi River, encompassing a number of neighborhoods between the French Quarter and the Jefferson Parish line. It remains an area of mixed residential and small commercial properties, with a wealth of 19th-century architecture. It includes part or all of Uptown New Orleans Historic District, which is listed on the National Register of Historic Places.

The French Quarter, also known as the Vieux Carré, is the oldest neighborhood in the city of New Orleans. After New Orleans was founded in 1718 by Jean-Baptiste Le Moyne de Bienville, the city developed around the Vieux Carré, a central square. The district is more commonly called the French Quarter today, or simply "The Quarter", related to changes in the city with American immigration after the 1803 Louisiana Purchase. Most of the extant historic buildings were constructed either in the late 18th century, during the city's period of Spanish rule, or were built during the first half of the 19th century, after U.S. purchase and statehood.