The Uzhhorod Synagogue is a former Orthodox Jewish synagogue located in Uzhhorod, in the present day Zakarpattia Oblast of western Ukraine. When it was established in 1904, it was located within the Austro-Hungarian Empire. The congregation worshipped in the Ashkenazi rite.

Uzhhorod is a city and municipality on the Uzh River in western Ukraine, at the border with Slovakia and near the border with Hungary. The city is approximately equidistant from the Baltic, the Adriatic and the Black Sea (650–690 km) making it the most inland city in this part of Europe. It is the administrative center of Zakarpattia Oblast (region), as well as the administrative center of Uzhhorod Raion (district) within the oblast. Population: 115,449.