Van Ness Bus Rapid Transit is a bus rapid transit (BRT) corridor on Van Ness Avenue in San Francisco, California, United States. The 1.96-mile (3.15 km) line, which runs between Mission Street and Lombard Street, has dedicated center bus lanes and nine stations. It was built as part of the $346 million Van Ness Improvement Project, which also included utility replacement and pedestrian safety features. Van Ness Bus Rapid Transit is used by several San Francisco Municipal Railway (Muni) lines including the 49 Van Ness–Mission, as well as three Golden Gate Transit routes.

Van Ness Avenue is a north–south thoroughfare in San Francisco, California. Originally named Marlette Street, the street was renamed in honor of the city's sixth mayor, James Van Ness.