Clube de Desportos Vasco da Gama is an Indian professional football club based in Vasco da Gama, Goa, part of the same named multi-sports club. Incorporated in 1951, the club is nicknamed "The Port Towners", and competes in the Goa Professional League.

Vasco da Gama, often shortened to Vasco, is a city in the state of Goa on the west coast of India. It is named after the Portuguese explorer Vasco da Gama. It is the headquarters of the Mormugão taluka (subdistrict). The city lies on the western tip of the Mormugao peninsula, at the mouth of the Zuari River, about 30 kilometres (19 mi) from Panaji, Goa's capital, 28 kilometres (17 mi) from Margao, the district headquarters and about 5 kilometres (3.1 mi) from Dabolim Airport.