Vermont Route 289 (VT 289) is a state highway located within the town of Essex, Vermont. It is a 3.94-mile-long (6.34 km) limited-access highway that extends from VT 2A southeast to VT 117 on the north bank of the Winooski River. Most of VT 289 is a two-lane undivided highway.

U.S. Route 2 (US 2) is a part of the United States Numbered Highway System that is split into two segments. Its eastern segment runs from Rouses Point, New York, to Houlton, Maine. In Vermont, US 2 extends 150.518 miles (242.235 km) from the New York state line in Alburgh to the New Hampshire state line in Guildhall. West of Vermont, US 2 continues into New York for another 0.87 miles (1.40 km) to an intersection with US 11 in Rouses Point. US 2 passes through the cities of Burlington and Montpelier as it traverses the state. The highway parallels Interstate 89 (I-89) between these two cities. The Burlington to Montpelier route was first laid out as a toll road in the early 19th century. It was later incorporated into the transcontinental auto trail known as the Theodore Roosevelt International Highway in 1919 before being designated as part of US 2 in 1926.