Virginia Eliza Poe was the wife of American writer Edgar Allan Poe. The couple were first cousins and publicly married when Virginia Clemm was 13 and Poe was 27. Biographers disagree as to the nature of the couple's relationship. Though their marriage was loving, some biographers suggest they viewed one another more like a brother and sister. In January 1842, she contracted tuberculosis, growing worse for five years until she died of the disease at the age of 24 in the family's cottage, at that time outside New York City.

Edgar Allan Poe was an American writer, poet, author, editor, and literary critic who is best known for his poetry and short stories, particularly his tales of mystery and the macabre. He is widely regarded as a central figure of Romanticism and Gothic fiction in the United States, and of American literature. Poe was one of the country's earliest practitioners of the short story, and is considered the inventor of the detective fiction genre, as well as a significant contributor to the emerging genre of science fiction. He is the first well-known American writer to earn a living through writing alone, resulting in a financially difficult life and career.