Virophage
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Virophages are small, double-stranded DNA viruses that require the co-infection of another virus. The co-infecting viruses are typically giant viruses. Virophages rely on the viral replication factory
Sputnik virofago
Genome organization of cultured virophages Genome representation of the virophages Sputnik, Zamilon, and Mavirus. Homologous genes are colored identically.
Giant virus
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A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum Nucleocytoviricota.
Virophage
…Virophages are small, double-stranded DNA viruses that require the co-infection of another virus. The co-infecting viruses are typically giant viruses. Virophages rely on the viral replication factory of the co-infecting giant virus for their own replication. One of the characteristics of virophages…
Cryo-EM images of the giant viruses CroV and APMV. (A) Cryo-electron micrograph of four CroV particles. (B) Single CroV particle with concave core depression (white arrow). (C) Single APMV particle. Scale bars in (A–C) represent 2,000 Å.
Several giant viruses (Megaklothovirus horridgei, Pithovirus sibericum, Klothovirus casanovai, and Mimivirus) compared to E. Coli bacterium and normal size virus (HIV)