Vologases V was King of Kings of the Parthian Empire from 191 to 208. As king of Armenia, he is known as Vologases II. Not much is known about his period of kingship of Armenia, except that he put his son Rev I on the Iberian throne in 189. Vologases succeeded his father Vologases IV as king of the Parthian Empire in 191; it is uncertain if the transition of power was peaceful or if Vologases took the throne in a civil war. When Vologases acceded the Parthian throne, he passed the Armenian throne to his son Khosrov I.

Vologases IV was King of Kings of the Parthian Empire from 147 to 191. He was the son of Mithridates V. Vologases spent the early years of his reign re-asserting Parthian control over the Kingdom of Characene. From 161 to 166, he waged war against the Roman Empire; although initially successful, conquering Armenia and Syria, he was eventually pushed back, briefly losing control of the Parthian capitals of Seleucia and Ctesiphon to the Romans. The Romans suffered heavy losses from a plague erupting from Seleucia in 166, forcing them to withdraw. The war ended soon afterward, with Vologases losing most of northern Mesopotamia to the Romans. He died in 191 and was succeeded by his son Vologases V.