"What's Up?" is a song by American rock group 4 Non Blondes, released in March 1993 by Interscope and Atlantic Records as the second single from their debut album, Bigger, Better, Faster, More! (1992). The song was written by lead singer Linda Perry and produced by David Tickle. It has gained popularity in the United States and in several European countries, peaking at number one in Austria, Belgium, Denmark, Germany, Iceland, Ireland, the Netherlands, Norway, Poland, Sweden, and Switzerland. The accompanying music video was directed by American film director Morgan Lawley and was also nominated in the category for Best Alternative Rock Video at the MTV Video Music Awards.

4 Non Blondes was an American rock band from San Francisco, active from 1989 to 1994. Their only album, Bigger, Better, Faster, More!, spent 59 weeks on the Billboard 200 and sold 1.5 million copies between 1992 and 1994. They hit the charts in 1993 with the release of the album's second single, "What's Up?".