Wilhelmina Cole Holladay was an American art collector and patron. She was the co-founder of the National Museum of Women in the Arts, and was awarded the National Medal of Arts in 2006.

The National Museum of Women in the Arts (NMWA), located in Washington, D.C., is "the first museum in the world solely dedicated" to championing women through the arts. NMWA was incorporated in 1981 by Wallace and Wilhelmina Holladay. Since opening in 1987, the museum has acquired a collection of more than 6,000 works by more than 1,000 artists, ranging from the 16th century to today. The collection includes works by Mary Cassatt, Alma Woodsey Thomas, Élisabeth Louise Vigée-LeBrun, and Amy Sherald. NMWA also holds the only painting by Frida Kahlo in Washington, D.C., Self-Portrait Dedicated to Leon Trotsky.