William Hepburn Russell (1812–1872) was an American businessman. He was a partner, along with Alexander Majors and William B. Waddell, in the freighting firm Russell, Majors, and Waddell and the stagecoach company the Central Overland California and Pikes Peak Express Company which was the parent company of the Pony Express. His public life is one of numerous business ventures, some successful and some failed. While Russell, described as a good-looking man, lived the majority of his life on the edge on the western frontier, he was always more at home in the upper-class settings of the East coast.

Alexander Majors was an American businessman, who along with William Hepburn Russell and William B. Waddell founded the Pony Express, based in St. Joseph, Missouri. This was one of the westernmost points east of the Missouri River from its upper portion beyond that state. It was a major supply point for migrants and pioneers headed west to Oregon Country.