Sai Kwan or Xiguan is an ancient town and an area in the Liwan district of Guangzhou, China, which was located west of the old walled city. The Thirteen Factories trading enclave was located on its southern shore and the Shamian enclave was constructed beside it. Xiguan continues to have a distinctive culture within Guangzhou and some residents speak a distinctive dialect of Cantonese.

Guangzhou is the capital and largest city of Guangdong province in southern China. Located on the Pearl River about 120 km (75 mi) north-northwest of Hong Kong and 145 km (90 mi) north of Macau, Guangzhou has a history of over 2,200 years and was a major terminus of the Silk Road.