Yellow Jack is a 1934 docudrama play starring James Stewart and produced by Guthrie McClintic that was later adapted into a 1938 Hollywood movie by the same title. Both were co-written by Sidney Howard and Paul de Kruif. The play is the work of Sidney Howard and is based on a chapter in Paul de Kruif's 1927 book Microbe Hunters.

James Maitland Stewart was an American actor. Known for his distinctive drawl and everyman screen persona, Stewart's film career spanned 80 films from 1935 to 1991. With the strong morality, which he portrayed both on and off the screen, he epitomized the "American ideal" in the mid-twentieth century. In 1999, the American Film Institute (AFI) ranked him third on its list of the greatest American male actors. He received numerous honors including the AFI Life Achievement Award in 1980, the Kennedy Center Honor in 1983, as well as the Academy Honorary Award and Presidential Medal of Freedom, both in 1985.