Zhuge Liang's Southern Campaign, also known as the War of Pacification in Nanzhong, was a military campaign which took place in 225 during the early Three Kingdoms period (220–280) of China. It was led by Zhuge Liang, the Imperial Chancellor of the state of Shu Han, against opposing forces in the Nanzhong region. The campaign was a response to rebellions started by local governors in the Nanzhong region and intrusions by the Nanman.

Zhuge Liang, also commonly known by his courtesy name Kongming, was a Chinese statesman, strategist, and inventor who lived through the end of the Eastern Han dynasty and the early Three Kingdoms period (220–280) of China. During the Three Kingdoms period, he served as the Imperial Chancellor of the state of Shu Han (221–263) from its founding in 221 and later as regent from 223 until his death in September or October 234.