Zinder Region is one of the seven regions of Niger; the capital of the region is Zinder. The region covers 145,430 km². It is the most populous province of Niger.

Zinder, formerly also spelled Sinder, is the third largest city in Niger, with a population of 235,605 as by the 2012 census. It is situated 861 km (535 mi) east of the capital Niamey and 240 km (150 mi) north of the Nigerian city of Kano.