Zoe Karbonopsina, also Karvounopsina or Carbonopsina, lit. 'with the Coal-Black Eyes', was an empress and regent of the Byzantine Empire. She was the fourth spouse of the Byzantine Emperor Leo VI the Wise and the mother of Constantine VII, serving as his regent from 913 until 919.

Leo VI, also known as Leo the Wise, was Byzantine Emperor from 886 to 912. The second ruler of the Macedonian dynasty, he was very well read, leading to his epithet. During his reign, the renaissance of letters, begun by his predecessor Basil I, continued; but the empire also saw several military defeats in the Balkans against Bulgaria and against the Arabs in Sicily and the Aegean. His reign also witnessed the formal discontinuation of several ancient Roman institutions, such as the separate office of Roman consul.